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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L5
All Species:
33.64
Human Site:
Y74
Identified Species:
56.92
UniProt:
Q9HCM4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCM4
NP_065960.2
733
81856
Y74
E
L
F
D
Q
I
M
Y
H
L
D
L
I
E
S
Chimpanzee
Pan troglodytes
XP_001157953
733
81845
Y74
E
L
F
D
Q
I
M
Y
H
L
D
L
I
E
S
Rhesus Macaque
Macaca mulatta
XP_001088764
726
81122
Y74
E
L
F
D
Q
I
M
Y
H
L
D
L
I
E
S
Dog
Lupus familis
XP_532028
914
101864
Y156
D
L
F
D
Q
I
V
Y
H
L
D
L
V
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGS1
731
81617
Y74
E
L
F
D
Q
I
M
Y
H
L
D
L
I
E
S
Rat
Rattus norvegicus
Q5FVG2
731
81700
Y74
E
L
F
D
Q
I
M
Y
H
L
D
L
I
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
F87
S
G
K
L
E
C
P
F
D
T
A
V
Q
L
A
Chicken
Gallus gallus
XP_422083
502
57358
Frog
Xenopus laevis
NP_001080234
498
57093
Zebra Danio
Brachydanio rerio
O57457
619
70690
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
Y89
F
L
Y
E
Q
V
F
Y
A
L
D
I
I
E
K
Honey Bee
Apis mellifera
XP_623974
809
90976
Y153
D
L
Y
E
Q
V
F
Y
S
L
D
L
I
E
K
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
E208
G
Q
T
P
D
V
A
E
Q
N
F
L
D
H
A
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
Y69
E
L
Y
D
Q
V
I
Y
S
L
D
V
I
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.2
39.8
N.A.
83.9
83.6
N.A.
56.5
56.6
54.4
28.5
N.A.
36.8
38.9
24.3
39.1
Protein Similarity:
100
99.3
96.3
52.1
N.A.
89.2
88.4
N.A.
65.1
62.2
60.9
44.7
N.A.
51.8
53.1
40.1
56.7
P-Site Identity:
100
100
100
73.3
N.A.
100
100
N.A.
0
0
0
0
N.A.
46.6
53.3
6.6
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
0
0
0
N.A.
73.3
80
20
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
8
0
8
0
0
0
15
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
50
8
0
0
0
8
0
65
0
8
0
0
% D
% Glu:
43
0
0
15
8
0
0
8
0
0
0
0
0
65
0
% E
% Phe:
8
0
43
0
0
0
15
8
0
0
8
0
0
0
0
% F
% Gly:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
43
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
43
8
0
0
0
0
8
58
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
22
% K
% Leu:
0
65
0
8
0
0
0
0
0
65
0
58
0
8
0
% L
% Met:
0
0
0
0
0
0
36
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
65
0
0
0
8
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
0
15
0
0
0
0
0
36
% S
% Thr:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
8
% T
% Val:
0
0
0
0
0
29
8
0
0
0
0
15
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
22
0
0
0
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _